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Seronegative RA and Genetic Predisposition

April 25, 2014 No comments Article

Genetics can explain why infections can trigger rheumatoid arthritis

The link above goes to a press release about a study by the Arthritis Research UK Centre for Genetics and Genomics at The University of Manchester. This kind of work is really important, and I suspect we will see major changes in the diagnosis and categorization of autoimmune and autoinflammatory diseases in the next decade. But it brings up some interesting ethical dilemmas. For example, knowing that there’s no cure, would you live your life differently if you were told your had a “RA gene” and that a viral or bacterial infection could bring on full-blown disease?

Abstract and full paper here.

Tags: genetics, news, research, rheumatoid arthritis, seronegative
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